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Journal Scan
March 2007
Validation of hemoglobin estimation using blood gas analyzer
Modern blood gas analyzers often have incorporated technology
that allows hemoglobin measurement on the same blood sample used to
measure pH, pCO2 and pO2.
Clinicians working in a UK neonatal intensive care department where
such an instrument was routinely used for blood gases were keen to
exploit the newly available...
Hemoglobins
Blood gases/acid-base
Neonatology
Journal Scan
March 2007
Is arterialized capillary blood a suitable alternative to arterial blood for measurement of pH, pCO2 and pO2?
Arterial blood is the standard sample for measurement of pH,
pCO2 and pO2, but
collection of arterial blood can be painful. Furthermore, it is a
procedure associated with some risk to the patient and can
therefore only be performed by trained, medically qualified staff.
Capillary blood collection by finger or...
Blood gases/acid-base
Preanalytical phase
Journal Scan
January 2007
Cord blood sampling for lactate must not be delayed
Blood gas analysis of umbilical cord blood provides the means
for establishing the acid-base status of babies at the time of
birth. If there is to be any delay in sampling, the portion of cord
from which the sample is to be taken should be double-clamped and
thereby isolated from the placenta.
Previous studies have...
Hemoglobins
Neonatology
Journal Scan
December 2006
Blood gas analyzers provide reliable bilirubin measurement
Modern blood gas analyzers have incorporated technology that
allows spectrophotometric measurement of bilirubin concentration on
the same whole-blood sample that is used to measure blood gas
parameters. A recent French multicenter study confirms the
reliability of this technique for measuring bilirubin during the...
Bilirubin
Point-of-care testing
Journal Scan
December 2006
Investigation of hypoglycemia in an intensive care setting
In 2001 a landmark study demonstrated that normalization of
blood glucose significantly reduces mortality and morbidity among
intensive care patients. Now 5 years on, strict control of blood
glucose concentration with insulin therapy is accepted as an
imperative of optimal intensive care in many hospitals around the...
Glucose
Journal Scan
December 2006
Reduced blood pH causes bleeding
Hemorrhage, due to a reduction in the coaguability of blood, is
a common cause of morbidity and mortality among trauma victims and
the critically ill in general. Reduced blood pH (acidosis) is also
common in these patient groups. Previous studies have shown that
acidosis is an independent risk factor for development...
Blood gases/acid-base
Coagulation/fibrinolysis
Journal Scan
December 2006
Temperature correction of blood gas results
Measurements of pH, pCO2 and
pO2 of arterial blood during blood gas analysis
are all made at normal body temperature, 37 °C. The sample is
warmed to that temperature prior to analysis. Blood gas analyzers
provide the option for these primary measurements to be
automatically "corrected" to the patient’s actual body...
Blood gases/acid-base
Preanalytical phase
Journal Scan
October 2006
Blood glucose and survival following myocardial infarction
Transient hyperglycemia (raised blood glucose concentration) is
a common feature of serious acute illness, including myocardial
infarction. For many years, this so-called "stress hyperglycemia"
was considered of little clinical significance unless it was
particularly severe (blood glucose > 12 mmol/L) or associated...
Glucose
Journal Scan
October 2006
Oxygen saturation immediately after birth
Pulse oximetry provides the means for continuous non-invasive
monitoring of oxygen saturation (SpO2). Although not
currently used for the purpose, recent international guidelines
suggest that pulse oximetry may be useful in the assessment of
newborns who require urgent resuscitative measures at the time of
birth....
Blood gases/acid-base
Neonatology
Journal Scan
October 2006
Measuring acid-base variables – is arterial blood essential?
Conventionally, arterial blood is sampled for blood gas
analysis, but if the purpose is to assess acid-base balance, venous
blood may be an acceptable alternative. That is the main conclusion
of a recently published study conducted at the intensive care units
of two Melbourne hospitals.
The objective of the study was ...
Blood gases/acid-base
Preanalytical phase