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Articles and journal scans about Bilirubin
Journal Scan
August 2018
A novel use of serum bilirubin measurement investigated
Bilirubin is a product of the hemoglobin catabolism that occurs principally in the spleen where red cells (that contain hemoglobin) are sequestered at the end of their approximate 120-day life. Bilirubin is transported in blood from the spleen to the liver where it is eliminated from the body in bile. Serum bilirubin...
Bilirubin
Journal Scan
August 2016
Modest change in bilirubin calibration has major effect in neonatal care
Phototherapy, the standard treatment for neonatal jaundice, is guided by age-related serum bilirubin concentration; the older the baby, the higher is the recommended triggering serum bilirubin concentration.
So that for example, UK guidelines state that for a full-term baby who is 12 hours old, phototherapy should be ...
Bilirubin
Neonatology
Journal Scan
July 2014
Raised serum bilirubin (jaundice) – a review of inheritable causes
Bilirubin is a waste product of hemoglobin catabolism that is excreted via the liver in bile.
Abnormal accumulation of this yellow pigment in blood results in jaundice. For adults and children, increased serum bilirubin and resulting jaundice is most commonly a signal of liver or biliary-tract disease; whilst for...
Neonatology
Bilirubin
Article
June 2013
How to optimize patient flow and outcome in ED - The impact of point of care
Emergency Department (ED) overcrowding is becoming an increasingly international issue.
Although the problem is not only resolved by ED change management (but rather requires a system-wide solution recognizing the complex interdependencies of consumer expectations, human resources, information systems immaturity and...
Point-of-care testing
Process optimization
Blood gases/acid-base
Electrolytes
Cardiac markers
Glucose
Hemoglobins
Bilirubin
D-dimer
Troponins
Journal Scan
January 2012
Breast milk jaundice - a review
Serum bilirubin estimation, which has for some years now been available on point-of-care analyzers, including blood gas analyzers, is probably the most frequently requested blood test in neonatal medicine.
This is because increased serum/plasma bilirubin concentration (hyperbilirubinemia) and consequent jaundice is...
Bilirubin
Neonatology
Journal Scan
July 2011
No resurgence of kernicterus
Increased serum bilirubin, clinically manifest as jaundice, is very common during the first week of life, affecting around 60 % of full-term babies and 85 % of babies born prematurely. For the vast majority this neonatal jaundice is a mild transitory phenomenon with no long-term consequences. The greatest fear...
Bilirubin
Neonatology
Article
January 2011
Critical values in laboratory medicine
The process of patient sample testing, whether performed in the clinical laboratory or at the point of care, is the sum of three distinct phases. The first is the preanalytical phase, which includes test selection as well as sample collection and handling.
The second is the analytical or measuring phase that...
Bilirubin
Electrolytes
Point-of-care testing
Blood gases/acid-base
Glucose
Lactate
Creatinine/urea
Hemoglobins
Kidneys/fluids
Article
December 2009
Pediatric considerations in critical value assignment
Critical values are those associated with imminent danger unless acted upon promptly. Critical value menus often include results that do not fit this definition, leading to highly variable practice in adult and pediatric laboratories.
Existing menus may be subdivided into more uniform tiers of severity: the highly...
Neonatology
Bilirubin
Blood gases/acid-base
Electrolytes
Glucose
Creatinine/urea
Journal Scan
October 2009
Neonatal jaundice - detection and treatment thresholds
Neonatal jaundice is the subject of two recent studies and an accompanying editorial, all published in the October issue of Archives of Disease in Childhood (Neonatal Edition). The aim of the first study was to determine if visual assessment of jaundice on day 2-3 of life is accurate in estimating serum bilirubin and...
Neonatology
Bilirubin
Journal Scan
January 2009
A comprehensive review of neonatal jaundice
All newborn babies have, by comparison with adults, a raised serum concentration of unconjugated (and therefore total) bilirubin, due principally to the transient increase in red cell destruction associated with the move from intrauterine support to physiological independence.
In close to half of all newborns the...
Bilirubin
Neonatology