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The discovery that D-dimer may be elevated in COVID-19 was first reported by physicians in Wuhan, China where the epidemic started.

Evidence of a potential role for D-dimer and Procalcitonin testing used to assess comorbidities of patients hospitalized with COVID-19

Dyspnea (alternative names: breathlessness and shortness of breath) is a common reason for individuals to seek medical help either in primary care or the hospital emergency room. The possible causes are legion, so that assessment of the patient complaining of breathlessness is a common and often difficult diagnostic...

The D-dimer blood test is a clinical laboratory test that is also increasingly available at the point of care, most often the hospital emergency room. Over the past decade or so the test has become established for emergency room assessment of patients suspected of suffering deep vein thrombosis or pulmonary embolism,...

This article first appeared in Pathology in Practice (Hobba H, Silver L. Evolution of POC testing. Pathology in Practice 2013; 14 [2]: 63) and is reproduced here by kind permission (www.pathologyinpractice.com). © 2013 kdm communications limited Point-of-care (POC) testing has allowed the pathology department in...

D-dimer testing can combined with assessment of pretest probability be used to rule out VTE in patients with a sufficiently low pretest probability of VTE. Patients with a negative D-dimer result can be ruled out, while patients with a positive D-dimer result need to have imaging performed for confirmatory diagnosis. ...

The management at the emergency department of patients presenting with symptoms of chest pain and/or acute dyspnea accounts for a substantial proportion of emergency care resources. In the work-up of these patients the blood measurements of cardiac troponins and brain natriuretic peptides are recommended by current...

D-dimers are protein products of cross-linked fibrin degradation that are present in the blood of most healthy individuals in only negligible amounts (of the order 100-200 ng/mL). As objective evidence of increased fibrinolysis, elevated blood concentration of D-dimer is by extension evidence of intravascular...

In a regional top-management decision, our laboratory was given the mission to control and quality assure all POCT activities in a regional network of 10 hospitals with emergency units. Based on previous work, new region-wide recommendations, procurements,  IT connectivity, services, training, accreditation (ISO...