Preterm, very-low-birth-weight babies require intensive laboratory testing, including frequent blood gas analysis, during the first few weeks of life. It has been estimated that the weekly blood loss associated with phlebotomy for blood testing can amount to as much as 30 % of the total blood volume of these tiny,...

A raised serum bilirubin (hyperbilirubinemia) and consequent jaundice is a common feature during the neonatal period; more than half of all newborns develop mild jaundice – with serum bilirubin rarely exceeding 150 µmol/L – during the first week or two of life. This transitory phenomenon usually resolves spontaneously ...

Supported by Pennsylvania Hospital Kernicterus Fund and the Eglin Fund In the late 1980s, the question whether bilirubin damaged the brain of healthy infants was unanswered. The absence of documented evidence influenced the formulation of the 1994 consensus-based guidelines...

Point-of-care testing (POCT) results, like other forms of laboratory data, hold potential hidden information that can be utilized to improve patient care.  The technique of extracting useful information from vast amounts of data is termed “data mining”. Technological solutions are now available to meet the challenges ...

The University College London Hospitals (UCLH) is one of the largest NHS trusts in England. The Elizabeth Garrett Anderson and Obstetric Hospital houses the Trust's gynecology, obstetric and neonatal services. At the neonatal unit, blood gas monitoring has historically been done by a combination of blood gas...

In 2001, Belgian professor Greet Van den Berghe, PhD, and her colleagues at the Leuven University Hospital began a small revolution with the publication of the 2001 study “Intensive insulin therapy in critically ill patients”. According to the study, tighter glucose control based on insulin therapy lowered rates of...

In 1998, Fleury Diagnostics, Brazil's most comprehensive center for diagnostic medicine and pathology with 1,600 employees and 2,500 patients a day, implemented its own system for managing documents necessary for certification and point-of-care testing (POCT) programs. The system was entirely developed in-house in the ...

Preanalytical errors are a significant source of medical errors that can jeopardize patient safety. Proper specimen labeling practices are critical components of effective and accurate patient identification.  These variables are now considered part of the preexamination process in the newest CLSI quality system...

Simple data-mining algorithms can be applied to point-of-care testing (POCT) data to document compliance of quality control, operator training and to identify potential preanalytical errors. Data can be manipulated to automate manual review and other laborious processes for identifying data trends, verifying...

Oxygen is one of the most widely used drugs in medicine, and especially so in the newborn period. In many cases, oxygen supplementation is needed and is life-giving, but we are also aware of its toxic effects. In spite of this, we still do not know exactly what is the correct way to administer this drug. It is a...