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Articles and journal scans about Blood gases/acid-base
Journal Scan
January 2016
On the value of umbilical cord blood base deficit measurement
A clinical requirement for determination of the pH and base deficit (BD) of umbilical-cord arterial blood has ensured a role for the blood gas analyzer in the delivery suite of obstetric units.
The principal objective of this testing in the minutes immediately after birth is to identify those babies who have been...
Blood gases/acid-base
Neonatology
Journal Scan
January 2016
Is central venous blood an acceptable sample for blood gas analysis?
Blood gas analysis involves measurement of three parameters: pH, partial pressure of carbon dioxide (pCO2) and partial pressure of oxygen (pO2). Derived (calculated from these measured values) parameters also generated during blood gas analysis include: bicarbonate (HCO3) concentration, base excess (BE) and oxygen...
Blood gases/acid-base
Preanalytical phase
Journal Scan
January 2016
Role of the kidneys in maintaining normal blood pH
The maintenance of blood pH within normal limits (7.35-7.45), called acid-base homeostasis, is a complex synergy involving three organs (lungs, kidneys and brain) as well as chemical buffers in blood and blood cells (erythrocytes). This vital physiologic process is the subject of a recent expert review article,...
Blood gases/acid-base
Kidneys/fluids
Article
January 2016
Temperature correction of blood gas and pH measurement - an unresolved controversy
The process of blood gas and pH measurement involves preheating the arterial blood sample to normal body temperature (37 °C) prior to measurement of pH, partial pressure of oxygen (pO2) and partial pressure of carbon dioxide (pCO2).
This ensures that results reflect in vivo temperature condition. A minority of...
Preanalytical phase
Blood gases/acid-base
Infection/sepsis
Article
October 2015
Pneumatic tube transport of blood samples – an update
The significance of good practice during the preanalytical phase of clinical laboratory investigation cannot be overemphasized. One aspect of the preanalytical phase – the transport of samples – is considered here; in particular the transport of samples via pneumatic tube systems.
This is an update of a previous...
Process optimization
Blood gases/acid-base
Preanalytical phase
Glucose
Hemoglobins
Journal Scan
October 2015
Acid-base disturbance in cirrhosis – a clinical study
Cirrhosis of the liver is associated with increased respiration (hyperventilation) and consequent hypocapnic respiratory alkalosis. The severity of this acid-base disturbance correlates with severity of cirrhosis as well as severity of the abnormal hyperdynamic systemic circulation that characterizes this irreversible ...
Blood gases/acid-base
Journal Scan
July 2015
D-lactic acidosis – a very rare form of metabolic acidosis explained
Health demands that the pH of blood is maintained within a narrow range (7.35-7.45). Monitoring this physiological imperative and detection of so-called acid-base disturbance, in which blood pH is either increased or decreased, is one of the principal clinical utilities of blood gas analysis.
Metabolic acidosis – one ...
Blood gases/acid-base
Lactate
Journal Scan
July 2015
A novel use for measurement of carboxyhemoglobin and methemoglobin
Blood gas analyzers often have an incorporated CO-oximeter that allows accurate determination of carboxyhemoglobin (COHb) and methemoglobin (MetHb) from the arterial blood sample submitted for routine blood gas analysis. For patients with suspected acute pulmonary embolism (PE), arterial blood gas analysis is often...
Blood gases/acid-base
Troponins
Journal Scan
April 2015
An introduction to acid-base disorders and interpretation of blood gases
Arterial blood gas analysis provides the means for assessment of two related physiological functions that are disturbed in a wide range of medical conditions.
The first is the facility of the lungs to simultaneously add inspired oxygen to blood and remove carbon dioxide from blood, prior to excretion in expired air...
Blood gases/acid-base
Journal Scan
April 2015
A rare cause of metabolic (lactic) acidosis highlighted
Lactic acidosis, the most common kind of metabolic acidosis, is characterized by reduced blood pH (usually <7.25) in association with marked increase in blood lactate (usually >5.0 mmol/L). Lactic acidosis has many possible causes but two broad etiological classes have been defined: type A (hypoxic) lactic acidosis and ...7.25)>
Blood gases/acid-base
Lactate