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Articles and journal scans about Lactate
Journal Scan
October 2013
Arterial versus venous lactate
Blood lactate concentration, a parameter often available at the point of care on blood gas analyzers, is useful for assessment of global tissue oxygenation among acutely/critically ill patients. The ”gold standard” sample for this assessment, as for blood gas analysis, is arterial blood.
Sampling of venous blood is...
Lactate
Quality assurance
Journal Scan
October 2011
Prognostic value of lactate measurement in very-low-birth-weight infants
For a number of years point-of-care blood lactate measurement has been used to predict outcome for patients suffering a range of critical illnesses. Now a recently published study suggests that this predictive value of lactate measurement can also be usefully applied to very-low-birth-weight (VLBW) neonates born...
Neonatology
Lactate
Journal Scan
April 2011
Metformin-associated lactic acidosis
Metformin is an oral hypoglycemic drug that has long been employed in the treatment of type 2 diabetes; it is particularly widely prescribed for those diabetics who are obese. Very rarely, metformin use results in severe lactic acidosis, most often occurring in patients with reduced renal function.
Although a very...
Lactate
Journal Scan
October 2010
Metformin toxicity
Metformin, a blood-glucose-lowering drug widely used for treatment of type 2 diabetes, is associated with risk of potentially fatal metabolic (lactic) acidosis. This can occur not only following overdose but also at therapeutic dose in patients with pre-existing renal or liver disease.
Results of arterial blood gas...
Blood gases/acid-base
Lactate
Journal Scan
December 2009
Lactate monitoring of the critically ill
Although measurement of serum lactate has an established role in
the monitoring of critically ill patients at many hospitals around
the world, the practice is by no means universal, reflecting a
controversy that still surrounds the topic. In short there remains
no consensual answer to the broad question: Should we...
Blood gases/acid-base
Lactate
Journal Scan
January 2009
Correcting metabolic acidosis - is it beneficial? Is it safe?
Metabolic acidosis is the most common disturbance of acid-base balance among the critically ill of all ages, usually due to increased lactate production consequent on inadequate tissue perfusion and/or hypoxemia. The condition is characterized by primary reduction in bicarbonate and pH revealed during arterial blood...
Lactate
Neonatology
Journal Scan
July 2008
Umbilical cord blood gases - a sampling effect
Umbilical cord blood gas analysis provides objective evidence of neonatal condition at birth; a particular utility of the test is to identify those babies who have suffered significant oxygen deficit prior to delivery. Traditional obstetric practice is to clamp the umbilical cord within seconds of delivery but some...
Lactate
Blood gases/acid-base
Neonatology
Preanalytical phase
Journal Scan
January 2008
Lactate measurement – point of care versus the laboratory
Lactate measurement is important for diagnostic and prognostic assessment of the critically ill. Traditionally, lactate has been measured on serum/plasma samples in the central laboratory, but modern blood gas and other point-of-care analyzers now provide the means for real-time monitoring of lactate on whole blood at ...
Point-of-care testing
Lactate
Journal Scan
April 2006
Severe metabolic acidosis - an unusual case history
A recently published paper describes the sad case history of a 17-year-old man who was brought, unconscious and totally unresponsive (Glasgow Coma Score 3), by ambulance to the emergency department of his local hospital. Blood gas analysis revealed he was suffering severe metabolic acidosis (pH 7.25, bicarbonate 9...
Lactate
Blood gases/acid-base