Measurement of glucose and lactate after 30 minutes of storage at room temperature can give deviating results of up to 5 % [1,2] and 29 % of the reference value [3] respectively [1,4], due to in vitro glycolysis Glucose and lactate are both important parameters in the surveillance of patients in critical care...

When it comes to acid base, there is no getting around the name of Ole Siggaard-Andersen (OSA). acutecaretesting.org talks to the world-renowned Danish professor, who has become a legend in the field of blood gas.

Minimizing costs? Quality assurance? Training? Simpler devices? acutecaretesting.org asked four healthcare professionals in Australia and New Zealand what they saw as the main challenges of POCT. Answers were broad in spectrum. Nevertheless, three challenges were (directly or indirectly) mentioned repeatedly:...

Monitoring of blood gases is essential in neonatal intensive care. Traditionally arterial samples have been considered the gold standard, but in critically ill neonates physiological changes can happen within minutes to a degree endangering the newborn. Clinicians can therefore not rely solely on intermittent...

Preanalytical errors are said to be the reason for up to 75 % [1] of all errors in laboratory medicine. The diagnostic consequences depend on the magnitude of the preanalytical error.  In worst case, these errors may lead to mistreatment of patients; in all cases, these errors are an extra workload for the hospital...

Non-invasive monitoring of oxygenation has become a standard procedure in neonatal critical care. Both transcutaneous pO₂ (tcpO₂) monitors and pulse oximeters involve methodological and practical issues that should be known to those using these devices in infants. tcpO₂ measurements are influenced by skin thickness, ...

That is the question the Hvidovre Hospital had to ask itself in May 2003, when the Danish National Board of Health and the Copenhagen Hospital Corporation appointed it to be one of the country's three key sites for receiving and treating SARS patients. Once appointed, the hospital began a painstaking process of...

Like many hospitals throughout the world, the Princess Royal Hospital in Sussex, England has set up a quality assurance (QA) scheme to verify the competency of glucose-meter operators. Their scoring system, however is anything but typical. Instead of relying solely on individual results, the system also uses...

Although blood glucose measurement is commonly performed, the use of a whole-blood sample introduces complications and compromise in terms of the assay principle, the method of calibration and the expression of results. Most point-of-care systems are calibrated against a method chosen by the manufacturer for...

The Directive is a complex and detailed document and in the following the author focuses on some of the items that are particularly important for the user to be aware of.  Most of the rules will apply to the manufacturers and the public and the users will take advantage of the rulings if they become aware of their...