Reprinted with permission from Elsevier from "Neonate capillary blood gas reference values", by Jocelyne Cousineau, Suzanne Anctil, Ana Carceller, Monique Gonthier and Edgard E. Delvin, CLINICAL BIOCHEMISTRY, Vol no 38, 2005, pp 905-907. Copyright 2005 by Canadian Society of Clinical Chemists. OBJECTIVES Because...

Millions of times every day, in a myriad of distinctive laboratories around this globe, front-line workers make the final decision on the quality of results they report. If they decide the quality is “OK”, patient results are released to impact clinical decisions, and proficiency values reflect the overall ability...

Effectively written policies and procedures can help contribute to an error-free POCT program. Sentara Healthcare has incorporated policy and procedure development into their safety program. It is coined Focus & Simplify and is about improving the effectiveness of work processes and procedure documentation.  Through ...

Assessment of patient acid-base status is one of the principal uses of arterial blood gas analysis. Disturbance of acid-base, usually the result of abnormal accumulation of metabolic acids, most notably lactic acid, is a relatively frequent finding among critically ill patients.  Base deficit (BD), a blood gas...

Hailed by UK diabetic expert Professor Harry Keen as "one of the most important studies ever done for people with diabetes" when it was published in 1993, this influential clinical study was conducted by the Diabetes Control and Complications Trial Research Group (DCCT).  It settled once and for all a debate that had...

Investment in medical research is expected to have a payback; we assume that with the passage of time increased knowledge and understanding of disease process will inevitably lead to improved treatment and better outcome. This optimistic paradigm has proved valid for some of the major killer diseases, including heart...

The results of the above trial suggest that administration of rFVIIa would reduce patient exposure to the perils of blood-product transfusion, which are only now being fully recognized.  Increased awareness of the morbidity and mortality associated with transfusion of blood products has led to the implementation of...

Massive hemorrhage is a major cause of morbidity and mortality among critically ill patients. Conventional treatment is based on surgical control of bleeding and transfusion of blood products including red cells, platelets and fresh frozen plasma. Despite optimal conventional care, bleeding sometimes proves impossible ...

Hemoglobin is the oxygen-carrying protein contained in red blood cells (erythrocytes). Although normally present in only trace amounts, there are three species of hemoglobin that cannot transport oxygen.  The three species, collectively called dyshemoglobins because of their functional redundancy, are methemoglobin,...

The collection of arterial specimens with glass syringes and immediate storage in iced water was the accepted industry standard for many years. Practice has changed over the past several years to blood gas sample collection in plastic syringes, likely due to the cost, safety and convenience of plastic. This change ...