Plasma sodium and chloride concentration are routinely measured using either a direct or indirect ion-specific electrode (ISE). Direct ISE is the technique employed in blood gas and most other point-of-care analyzers whereas indirect ISE is used in the majority of biochemistry profiling analyzers sited in central...

The critical significance of the preanalytical phase of blood testing is highlighted by the tragically fatal case of an intensive-care patient who was given an inappropriately high dose of insulin following a falsely high blood glucose result. The patient was recovering from multiple organ failure following surgery in ...

In most hospitals, the amount of nursing time spent on actual patient care is only 33 %, while problem solving consumes 40 % of their time. That’s the bad news. The good news is that inverting this ratio may be easier than you think.  According to Dr John Kenagy and David Sundahl of the US-based Kenagy & Associates,...

Blood gas analysis is a complex field that has a direct impact on patient care in a critical care environment. Healthcare professionals consistently emphasize high-quality results in order to properly treat patients, and recognize the need and usefulness of quality standards.  Using a path-of-workflow analysis as part ...

Technology is available worldwide to help us carry out diversified tasks and work in an easier, faster, and more efficient way.  Furthermore, technology can help us prevent analyzer downtime and failures that may have serious consequences for both business and patients. This article gives an overview of some of the...

The significance of good practice during the pretesting phase of clinical laboratory investigation cannot be  overemphasized. The production of high-quality, accurate results which are clinically useful depends as much on practice before the patient’s sample reaches the laboratory as it does on the analytical phase...

Reprinted and translated by permission of Danske Bioanalytikere, dbio from "Fra hæl eller håndryg", by Jytte Kristensen, dbio, vol no 4, 2007, pp 8-11. Copyright 2007 by dbio. Translated by Radiometer Medical ApS. Norwegian and Danish biomedical laboratory scientists disagree on best practice when collecting blood...

Clinical laboratories should have a policy mandating staff involved in analysis of patient samples to convey critical results to clinical staff urgently, usually by telephone. A critical result has been defined as a result "at such variance with normal as to be life threatening, unless something is done promptly, and...

Accurate blood gas results depend on a homogeneous blood sample and the necessity for thorough mixing of samples is reflected in written standard operating procedures for blood gas analysis. The results of a recent study suggest, however, that manual mixing techniques routinely used may be inadequate in achieving a...

Acid-base physiology and significance of blood gas results are topics that many students find daunting. Their difficulty is not aided by the non-standard abbreviations used to indicate partial pressure of a gas. The issue is highlighted in a recent letter to the journal Clinical Chemistry.  The authors cite the...