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Article
April 2004
Setting the record straight on shunt
The understanding and management of ventilation-perfusion (V/Q) relationships represents a cornerstone of intensive care unit (ICU) patient management.
The physiologic shunt calculation can reliably reflect the degree of gas exchange attributable to intrapulmonary disease or intracardiac shunting regardless of other ...
Blood gases/acid-base
Hemoglobins
Article
April 2004
The merit of routine cord blood measurement at birth
Cord blood ph measurement at birth, using relatively simple and non-invasive methods, provides obstetricians and perinatologists with an objective and sensitive measure for the condition of the infant during the final stage of birth.
As long as certain criteria are observed, the reported values are reliable. Routine ...
Neonatology
Blood gases/acid-base
Lactate
Article
April 2004
Multiprofile blood gas method comparison studies
Numerous method comparison studies of blood gas analyzer methods have been published in the literature; unfortunately, several studies show flaws in one or several aspects of experimental design, execution, statistical analysis or interpretation of results. The most common flaw seems to be an inability to separate...
Preanalytical phase
Point-of-care testing
Quality assurance
Article
March 2004
Transcutaneous monitoring: back to the future - An important adjunct to care during high frequency oscillatory ventilation
High frequency oscillatory ventilation (HFOV) is often used in neonatal intensive care. HFOV has been shown to decrease bronchopulmonary dysplasia [1,2,3] in preterm infants and to be very effective in the treatment of persistent pulmonary hypertension of the newborn when used in conjunction with inhaled nitric oxide ...
Neonatology
Hemoglobins
Article
February 2004
The new CLIA quality control regulations and blood gas testing
In the U.S. all clinical laboratory determinations, including blood gas testing performed at point of care (POC) or in the central laboratory, is regulated by the Clinical Laboratory Improvement Amendments of 1988 (CLIA).
Congress passed CLIA to ensure accurate, reliable, and timely test results regardless of...
Point-of-care testing
Blood gases/acid-base
Quality assurance
Article
January 2004
Useful tips to avoid preanalytical errors in blood gas testing: metabolites
Measurement of glucose and lactate after 30 minutes of storage at room temperature can give deviating results of up to 5 % [1,2] and 29 % of the reference value [3] respectively [1,4], due to in vitro glycolysis
Glucose and lactate are both important parameters in the surveillance of patients in critical care...
Preanalytical phase
Glucose
Quality assurance
Lactate
Blood gases/acid-base
Article
January 2004
Monitoring fluid and electrolyte therapy in the newborn intensive care unit
Fluid and electrolyte management is an important and challenging part of the management of any very premature or critically ill newborn. The newborn's ability to maintain fluid and electrolyte homeostasis in the face of the vagaries of extrauterine life is compromised by immature renal function.
The very premature...
Preanalytical phase
Neonatology
Glucose
Lactate
Creatinine/urea
Article
January 2004
Ole Siggaard-Andersen: The man behind the legend
When it comes to acid base, there is no getting around the name of Ole Siggaard-Andersen (OSA). acutecaretesting.org talks to the world-renowned Danish professor, who has become a legend in the field of blood gas.
Blood gases/acid-base
Lactate
Article
January 2004
What is EQA
External Quality Assessment (EQA) in medical laboratories have evolved over the past 50 years to provide more sophisticated systems compared with the simple participants’ analytical performance evaluation of earlier years.
There are clear distinctions between the proficiency testing schemes and the evolved External...
Quality assurance
Article
January 2004
Transcutaneous monitoring of pO2 and pCO2 in neonates - a blessing or a burden?
Monitoring of blood gases is essential in neonatal intensive care. Traditionally arterial samples have been considered the gold standard, but in critically ill neonates physiological changes can happen within minutes to a degree endangering the newborn.
Clinicians can therefore not rely solely on intermittent...
Neonatology