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Articles by J. Kofstad
Showing articles by "J. Kofstad"
Article
October 2012
100 years of blood gas and acid base analysis in clinical medicine
The term acidosis was first mentioned in the medical literature in 1898 in connection with the description of diabetic ketoacidosis. Alkalosis was first used in human medicine in 1922 by the English physiologist J. S. Haldane; it had been used in veterinary medicine somewhat earlier.
In 1870, the Norwegians C. M....
Blood gases/acid-base
Glucose
Lactate
Hemoglobins
Article
July 2003
All about base excess – to BE or not to BE
In 1948, Singer and Hastings introduced the concept of buffer base (BB). The change in BB from "normal" was called deltaBB (ΔBB). This change in BB was an expression of the non-respiratory (metabolic) component of an acid-base disturbance. This was the first approximation to base excess.
In the 1950s, Astrup and...
Blood gases/acid-base
Hemoglobins