50-75 % of all newborns develop jaundice during their first week of life [1,2,3]. The decision behind which treatment is necessary and when it should be initiated is based upon a measurement of the concentration of total bilirubin (ctBil) in serum, plasma or whole blood.  It is therefore obvious that it is important...

Blood gas analysis at the point of care plays an important role during and after an open-heart surgery. acutecaretesting.org recently talked to Prof. Knut Kleesiek, MD, Director of the Institute for Laboratory and Transfusion Medicine of the Heart and Diabetes Center North Rhine-Westphalia in Germany, to find out more ...

Arterial blood gas analysis with the measurement of the partial pressure of carbon dioxide in arterial blood may be performed in the Pediatric ICU to evaluate the efficacy of ventilation or evaluate acid-base status. Although the direct measurement of PaCO₂ remains the gold standard, it provides only a single...

Oxygen saturation can be obtained from many different types of devices. This range of choices causes some confusion as to definitions of measured variables and their clinical interpretation. This article gives some historical background and describes the two different ways saturation can be obtained from a blood gas ...

Arterial blood gas analysis is a test most frequently performed on critically ill patients in the emergency room, recovery room and intensive care unit by nursing staff. One of the main purposes of the test is assessment of acid-base status, which is often disturbed during critical illness. This article is intended...

Cord blood ph measurement at birth, using relatively simple and non-invasive methods, provides obstetricians and perinatologists with an objective and sensitive measure for the condition of the infant during the final stage of birth.  As long as certain criteria are observed, the reported values are reliable. Routine ...

Numerous method comparison studies of blood gas analyzer methods have been published in the literature; unfortunately, several studies show flaws in one or several aspects of experimental design, execution, statistical analysis or interpretation of results. The most common flaw seems to be an inability to separate...

Apgar scores and umbilical artery pH have traditionally been used as objective measures of neonatal asphyxia. According to the literature, the practice of cord gas analysis varies greatly both between and within countries - whether analysis is performed, whether it is routine at all births and why it is performed...

High frequency oscillatory ventilation (HFOV) is often used in neonatal intensive care. HFOV has been shown to decrease bronchopulmonary dysplasia [1,2,3] in preterm infants and to be very effective in the treatment of persistent pulmonary hypertension of the newborn when used in conjunction with inhaled nitric oxide ...

External Quality Assessment (EQA) in medical laboratories have evolved over the past 50 years to provide more sophisticated systems compared with the simple participants’ analytical performance evaluation of earlier years.  There are clear distinctions between the proficiency testing schemes and the evolved External...