Intensive intravenous insulin therapy directed at maintaining blood glucose concentration within tight normal limits (4.4–6.1 mmol/L) is now a standard of care for the critically ill. This requires frequent point of care blood glucose testing.   For appropriate intravenous insulin dosing it is vital that the chosen...

The notion that orange juice may be harmful to health seems counterintuitive if not bizarre, but as a recently published case history reveals, orange juice contains significant amounts of potassium and ingestion of large quantities of orange juice can lead to hyperkalemia of sufficient severity to threaten life.  Over ...

Maintaining lasting progress in laboratory test utilization is difficult to do without a reminder tool for providers. Since implementation of a quarterly physician report card in 2003, we have seen sustained improvement in the ordering of wellness tests in an ambulatory care network in the United States for over four...

There are few medical diagnoses that depend solely on the result of a single blood test, but diabetes mellitus, which is defined by concentration of circulating glucose, is one that does. Quite apart from its long established role in diagnosis as well as life-long monitoring of diabetes, measurement of circulating...

The integrity and function of all cells depend on an adequate supply of oxygen. Severe acute illness is frequently associated with inadequate tissue perfusion and/or reduced amount of oxygen in blood (hypoxemia) leading to tissue hypoxia.  If not reversed, tissue hypoxia can rapidly progress to multiorgan failure and ...

In 2005, acutecaretesting.org interviewed Dr Michael Astion, an active spokesperson for patient safety and reduction of lab errors, on the main issues surrounding the topic. Since then, a lot has changed… or has it? In a follow-up interview with Astion, acutecaretesting.org gauges the status of patient safety year...

The critical significance of the preanalytical phase of blood testing is highlighted by the tragically fatal case of an intensive-care patient who was given an inappropriately high dose of insulin following a falsely high blood glucose result. The patient was recovering from multiple organ failure following surgery in ...

Reprinted and translated by permission of Danske Bioanalytikere, dbio from "Fra hæl eller håndryg", by Jytte Kristensen, dbio, vol no 4, 2007, pp 8-11. Copyright 2007 by dbio. Translated by Radiometer Medical ApS. Norwegian and Danish biomedical laboratory scientists disagree on best practice when collecting blood...

In the majority of U.S. healthcare institutions, patient wristbands do not contain barcodes, creating a situation where patient data is manually typed into a database or point-of-care device, leaving plenty of room for error.  In light of error statistics issued by the United Kingdom’s National Patient Safety Agency...

Mock inspections are a great way to prepare for real-life inspections from regulatory agencies such as CAP and JCAHO. But where do you start? And most importantly, what should you look for? Lou Ann Wyer, Clinical Specialist, POCT at the Virginia-based Sentara Laboratory Services and Theresa Kulik, Point-of-care...