Reprinted with permission from Elsevier from "Neonate capillary blood gas reference values", by Jocelyne Cousineau, Suzanne Anctil, Ana Carceller, Monique Gonthier and Edgard E. Delvin, CLINICAL BIOCHEMISTRY, Vol no 38, 2005, pp 905-907. Copyright 2005 by Canadian Society of Clinical Chemists. OBJECTIVES Because...

Hailed by UK diabetic expert Professor Harry Keen as "one of the most important studies ever done for people with diabetes" when it was published in 1993, this influential clinical study was conducted by the Diabetes Control and Complications Trial Research Group (DCCT).  It settled once and for all a debate that had...

Iatrogenic phlebotomy loss resulting from the intensive clinical monitoring in the weeks immediately following birth remains the primary cause of neonatal anemia and the need for red-blood-cell (RBC) transfusion. Reducing RBC transfusion needs in the neonatal intensive care unit (NICU) requires new approaches for...

Laboratorians need to take ownership of errors, identifying, analyzing and reducing them, thereby increasing patient safety. A Client Services Department, customer care representatives, a service improvement coordinator, “morning report”, electronic error tracking and reporting mechanisms, point-of-care support...

Capillary blood sampling via a heel lance is the most common procedure performed in hospitalized neonates. Adequate training and supervision of the personnel performing the procedure is necessary to prevent/minimize inadequate sampling volumes, false laboratory results and complications such as pain. Efforts should be ...

Blood gases are measured from an arterial blood sample to evaluate the respiratory adequacy and oxygen status of the critically ill patient. For the adult patient, the arterial blood is sampled either by arterial puncture or from an indwelling catheter. In neonates and children, the wish to minimize iatrogenic blood...

Disturbance of normal acid-base balance is a defining feature of diabetic ketoacidosis (DKA), the acute and potentially life-threatening complication of diabetes that results from severe insulin deficiency. The cause of the acidosis in such cases is abnormal accumulation in blood of the two ketoacids, acetoacetate and ...

Point-of-care testing (POCT) results, like other forms of laboratory data, hold potential hidden information that can be utilized to improve patient care.  The technique of extracting useful information from vast amounts of data is termed “data mining”. Technological solutions are now available to meet the challenges ...

In 2001, Belgian professor Greet Van den Berghe, PhD, and her colleagues at the Leuven University Hospital began a small revolution with the publication of the 2001 study “Intensive insulin therapy in critically ill patients”. According to the study, tighter glucose control based on insulin therapy lowered rates of...

Simple data-mining algorithms can be applied to point-of-care testing (POCT) data to document compliance of quality control, operator training and to identify potential preanalytical errors. Data can be manipulated to automate manual review and other laborious processes for identifying data trends, verifying...