Iatrogenic phlebotomy loss resulting from the intensive clinical monitoring in the weeks immediately following birth remains the primary cause of neonatal anemia and the need for red-blood-cell (RBC) transfusion. Reducing RBC transfusion needs in the neonatal intensive care unit (NICU) requires new approaches for...

Capillary blood sampling via a heel lance is the most common procedure performed in hospitalized neonates. Adequate training and supervision of the personnel performing the procedure is necessary to prevent/minimize inadequate sampling volumes, false laboratory results and complications such as pain. Efforts should be ...

Blood gases are measured from an arterial blood sample to evaluate the respiratory adequacy and oxygen status of the critically ill patient. For the adult patient, the arterial blood is sampled either by arterial puncture or from an indwelling catheter. In neonates and children, the wish to minimize iatrogenic blood...

Preterm, very-low-birth-weight babies require intensive laboratory testing, including frequent blood gas analysis, during the first few weeks of life. It has been estimated that the weekly blood loss associated with phlebotomy for blood testing can amount to as much as 30 % of the total blood volume of these tiny,...

A raised serum bilirubin (hyperbilirubinemia) and consequent jaundice is a common feature during the neonatal period; more than half of all newborns develop mild jaundice – with serum bilirubin rarely exceeding 150 µmol/L – during the first week or two of life. This transitory phenomenon usually resolves spontaneously ...

Supported by Pennsylvania Hospital Kernicterus Fund and the Eglin Fund In the late 1980s, the question whether bilirubin damaged the brain of healthy infants was unanswered. The absence of documented evidence influenced the formulation of the 1994 consensus-based guidelines...

The University College London Hospitals (UCLH) is one of the largest NHS trusts in England. The Elizabeth Garrett Anderson and Obstetric Hospital houses the Trust's gynecology, obstetric and neonatal services. At the neonatal unit, blood gas monitoring has historically been done by a combination of blood gas...

Oxygen is one of the most widely used drugs in medicine, and especially so in the newborn period. In many cases, oxygen supplementation is needed and is life-giving, but we are also aware of its toxic effects. In spite of this, we still do not know exactly what is the correct way to administer this drug. It is a...

Almost as soon as healthcare providers began ventilating neonates with respiratory distress syndrome, the problem of chronic lung disease began. How to manage these children in a way to promote lung growth and disease-free survival has been the question for those involved in the care of these infants since that time....

About half of all newborn infants born at term develop jaundice during their first days of life, and the lower the gestational age the more frequent the jaundice is. Newborns develop hyperbilirubinemia because of a large bilirubin production, low hepatic excretion and enterohepatic recirculation. At birth the newborn ...